antihistamine 1 — TargetMol Chemicals

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Search Results for " antihistamine 1 "

Compounds

Cat No.	Product Name	Synonyms	Targets
T10335	Antihistamine-1		P450
	Antihistamine-1 is an H1-antihistamine (Ki: 6.9 nM) with acceptable blood-brain barrier penetration and also an inhibitor of CYP2D6 and hERG channel (IC50s: 5.4 and 0.8 μM).		P450
T0059	Diphenylpyraline hydrochloride	4-Diphenylmethoxy-1-methylpiperidine hydrochloride	Histamine Receptor
	Diphenylpyraline hydrochloride (4-Diphenylmethoxy-1-methylpiperidine hydrochloride) is used in the treatment of Parkinsonism.It is a first-generation antihistamine with anticholinergic effects, functions as a dopamine re...		Histamine Receptor
T9353	OXOMEMAZINE		AChR , Histamine Receptor
	Oxomemazine is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic activity. Oxomemazine is a selective antagonist of mycotoxins M1 receptors, showing high (Ki=84 nM, M1 receptors) and low ...		AChR , Histamine Receptor
T36949	Niaprazine		5-HT Receptor , Adrenergic Receptor , Histamine Receptor
	Niaprazine is a histamine H1-receptor antagonist with marked sedative properties. Niaprazine has antihistamine and antiserotonin activities and can be used for sleep disorder research[1][2]. Niaprazine exhibits a low aff...		5-HT Receptor , Adrenergic Receptor , Histamine Receptor
T60864	Sequifenadine
	Sequifenadine has the potential in researching of inflammatory eye disease with allergic symptoms that is a H1-antihistamine [1] [2].
T61088	Propiomazine
	Propiomazine is an orally active antihistamine agent that possesses sedative properties. It finds utility in insomnia research [1] [2].
T60391	Phenyltoloxamine
	Phenyltoloxamine (Bistrimin) is an antihistamine agent with sedative and analgesic effects. Phenyltoloxamine also has potent Sigma-1 receptor binding affinity with Ki of 160 nM [1] [2] [3].
T60424	Phenindamine
	Phenindamine (Nu 1504) is an H1-receptor antagonist which is antihistamine[1].
T36945	Cetirizine Impurity C
	Cetirizine Impurity C is an impurity of Cetirizine. Cetirizine is a second-generation antihistamine and the carboxylated metabolite of hydroxyzine. It acts as a specific, orally active, and long-acting antagonist of the ...
T61013	Bromodiphenhydramine
	Bromodiphenhydramine (Ambodryl) has antimicrobial activities which can be used in the cutaneous allergies research. Bromodiphenhydramine is an effective antihistamine that can inhibit a large number of Gram-negative and ...
T60366	Epinastine
	Epinastine (WAL801), a potent, selective, and orally-active antihistamine and mast cell stabilizer, functions as a histamine H1 receptor antagonist. It also inhibits IL-8 release from human eosinophils, showcasing antial...
T75276	Dexbrompheniramine
	Dexbrompheniramine, an orally active H1 receptor antagonist (antihistamine), mitigates the impacts of the natural chemical histamine in the body. It is utilized in the study of hay fever and urticaria [1].
T73933	Cetirizine methyl ester
	Cetirizine methyl ester, an impurity of Cetirizine, serves as a specific, orally active, and long-acting histamine H1-receptor antagonist. As a second-generation antihistamine and the carboxylated metabolite of hydroxyzi...
T73962	Cetirizine Impurity C dihydrochloride
	Cetirizine Impurity C dihydrochloride, a specific impurity of Cetirizine, is associated with a second-generation antihistamine that serves as the carboxylated metabolite of hydroxyzine. This compound acts as a specific, ...
T60843	Brompheniramine
	Brompheniramine ((±)-Brompheniramine) is a potent and orally active alkylamine class antihistamine. Brompheniramine is a selective antagonist of histamine H1 receptor (Kd = 6.06 nM). Brompheniramine can be used in the re...